• Irvine K, Stirling R, Hume D, Kennedy D (2005). "Rasputin, more promiscuous than ever: a review of G3BP". Int. J. Dev. Biol. 48 (10): 1065–77. doi:10.1387/ijdb.041893ki. PMID 15602692. • Onno M, Nakamura T, Hillova J, Hill M (1993). "Rearrangement of the human tre oncogene by homologous recombination between Alu repeats of nucleotide sequences from two different chromosomes". Oncogene. 7 (12): 2519–23. PMID 1461655. WebMar 14, 2024 · In contrast to WT U2OS cells, ectopic expression of ZBP1 and RIPK3 in G3bp1/2 −/− U2OS cells did not render the cells susceptible to arsenite-induced death. Furthermore, stress granule formation was restored in G3bp1/2 −/− U2OS cells reconstituted with G3BP1 and ectopically expressing ZBP1 and RIPK3 (Fig. 2I and fig. …
Canonical cellular stress granules are required for arsenite-induced ...
WebJan 6, 2024 · We further show that norovirus evades the stress granule response in a novel way by isolating and characterising the G3BP1 interactome for the first time in the context of a viral infection. ... Branca RM, Ivanov P, Anderson P. Phosphorylation of G3BP1-S149 does not influence stress granule assembly. J Cell Biol. 2024;218(7):2425–32. pmid ... WebApr 16, 2024 · The central node of this network is G3BP1, which functions as a molecular switch that triggers RNA-dependent LLPS in response to a rise in intracellular free RNA … suing an llc in texas
G3BP1 - Wikipedia
WebJan 30, 2024 · Phosphorylation within the IDRs regulates the propensity of G3BP1 to undergo phase separation and thus regulate SG dynamics . SGs sequester stalled ribosomal complexes that lacked a ternary complex. SGs can stabilize certain mRNAs that collect within them until the stress can be resolved or target others for degradation within … WebMar 21, 2024 · RASA1-dependent phosphorylation of Ser-149 induces a conformational change that prevents self-association. Dephosphorylation after HRAS activation is required for stress granule assembly. Ser-149 phosphorylation induces partial nuclear localization. Q13283-G3BP1_HUMAN; Arg-435 is dimethylated, probably to asymmetric … WebSep 29, 2024 · Depletion of G3BP1 significantly attenuated the activation of NF-κB signaling pathway. ... our results demonstrate that SVV induces transient SG formation in an eIF2α phosphorylation and PKR ... suing a prosecutor for misconduct