WebmSMART stands for Stratification for Myeloma and Risk-Adapted Therapy, which are continuously updated Mayo Clinic multiple myeloma treatment approach guidelines. We purposely chose a non-English word — an acronym — for the guidelines, so it would be easily internet searchable. Web1 ian. 2008 · High-dose therapy consists of 3 to 6 courses of a dexamethasone alone or combined with vincristine-adriamycin (VAD) to reduce the tumor burden and the plasma …

Drug Therapy for Multiple Myeloma - American Cancer Society

WebIn patients with NDMM or RMM, induction with DARA plus CyBorD followed by DARA alone as maintenance therapy resulted in durable and deep responses, with a 3-year PFS rate of 70%, regardless of ASCT status. No new safety concerns were identified with longer follow up. Keyword(s): Induction chemotherapy, Multiple myeloma http://mdedge.ma1.medscape.com/hematology-oncology/article/135809/multiple-myeloma/expanded-drug-combinations-produce-best-myeloma thibaud soulhat

Impact of maintenance therapy post autologous stem cell

Web12 apr. 2024 · Many CARs targeting solid tumors are currently under clinical evaluation, but they are at early stages and a number of fatal events have been reported for CAR-T cell therapies targeting TAAs such ... Web21 feb. 2024 · Patients with symptomatic myeloma are treated with combinations of active agents, typically one that contains a proteasome inhibitor and an immunomodulatory imide drug (IMiD), following which eligible patients often proceed to high-dose chemotherapy in combination with autologous stem cell transplantation (ASCT). Web21 apr. 2024 · Over the last few years, there has been great progress in the treatment of multiple myeloma (MM), ... Induction therapy, given before ASCT, has several goals: (1) to achieve a fast control of the disease; (2) to induce high response rates (if possible, high rates of minimal residual disease [MRD] negativity), with minimal toxicity, so that ... sage online login accountants