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Xylazine is a pharmaceutical drug used for sedation, anesthesia, muscle relaxation, and analgesia in animals such as horses, cattle, and other non-human mammals. Veterinarians also use xylazine as an emetic, especially in cats. It is an analog of clonidine and an agonist at the α2 class of … See more Xylazine was discovered as an antihypertensive agent in 1962 by Farbenfabriken Bayer in Leverkusen, Germany. Results from early human clinical studies confirmed that xylazine has several See more Xylazine is widely used in veterinary medicine as a sedative, muscle relaxant, and analgesic. It is frequently used in the treatment of See more Pharmacodynamics Xylazine is a potent α2 adrenergic agonist. When xylazine and other α2 adrenergic receptor agonists are administered, they distribute throughout the body within 30–40 minutes. Due to xylazine's highly lipophilic nature, … See more • McCurnin DM, Bassert JM (2002). Clinical Textbook for Veterinary Technicians (5th ed.). Philadelphia, PA: Saunders. • "Rompun Homepage". Bayer Healthcare. 2005. Archived from the original on 2007-03-02. See more In animals, xylazine may be administered intramuscularly or intravenously. As a veterinary anesthetic, xylazine is typically only administered once for intended effect before or during surgical procedures. Alpha-2 antagonists such as atipamezole and See more Since the early 2000s, xylazine has become popular as a drug of abuse in the United States and Puerto Rico. Xylazine's street name in … See more
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