WebJan 21, 2024 · 直接调控,直接作用的位点目前发现有:对STMN1基因（该基因编码的Stathmin蛋白被发现参与自噬调控），DRAM2，IRGM，线粒体自噬受体FUNDC1和NIX等.间接调控，即通过对细胞分子通路中重要的调控性蛋白进行调控，从而间接地调控自噬的过程。 WebOp18／stathmin信号调控的研究进展. 摘 要：Op18/stathmin是一种小分子磷蛋白，通过整合体内外不同信号影响微管动力学变化，从而影响细胞周期，与细胞生长、增殖、分化等密切相关；对肿瘤细胞恶性表型的维持、转移与侵犯等也都至关重要，是一个有望在肿瘤治疗 ...
Stathmin 1 靶点蛋白 抗体药物 临床药物信息
WebAug 19, 2024 · 2．2 Stathmin蛋白与肿瘤的关系 Belletti等 ¨在骨肉瘤中发现 Stathmin活动影 Stathmin蛋白作为细胞信号转导分子在细胞分 响肉瘤细胞形状、运动和转移潜能。. St~hmin刺激 化、组织再生与修复、尤其在恶性肿瘤发生、发展及 细胞运动中，并通过细胞外基质增加转移潜能 ... WebStathmin蛋白_一个潜在的肿瘤标志物. 。. stathm in. 还包括大量的转录因子识别序列 : 2 个 AP 2 位点 , 5 个 GC 2 盒和 4 个 E2F位点 [ 5 ] 。. stathm in蛋白能结合微管蛋白 ,作为 一个基本的微管解离蛋白参与微管和纺锤体的组装和活性 调节 。此外 , 它还能和多种蛋白结合 ... blue microphones mo fi
家蚕F box only蛋白BmFBXO21的抗体制备和定位分析-卡了网
http://med.wanfangdata.com.cn/Paper/Detail?id=DegreePaper_D800978&dbid=WF_XW Web3款als新药迎来不同命运 参比制剂查询系统提供是一家提供参比制剂全球查询网站，专业提供参比制剂，对照药品，国外上市药品，原研制剂，为客户提供参比制剂选择查询、一次性进口参比制剂信息、全球参比免费查询一站式服务。 Stathmin is a ubiquitous phosphorylated protein which makes it act as an intracellular relay for diverse regulatory pathways, functioning through a variety of second messengers. Its phosphorylation and gene expression are regulated throughout development [11] and in response to extracellular … See more Stathmin, also known as metablastin and oncoprotein 18 is a protein that in humans is encoded by the STMN1 gene. Stathmin is a highly conserved 17 kDa protein that is crucial for the regulation of the cell See more Stathmin, and the related proteins SCG10 and XB3, contain a N-terminal domain (XB3 contains an additional N-terminal hydrophobic region), … See more Stathmin interacts with two molecules of dimeric α,β-tubulin to form a tight ternary complex called the T2S complex. One mole of stathmin … See more Mice without stathmin have deficiency in innate and learned fear. Stathmin−/− females do not assess threats well, leading to lack of innate parental care and adult social … See more The function of Stathmin is to regulate the cytoskeleton of the cell. The cytoskeleton is made up of long hollow cylinders named microtubules. These microtubules are made up of alpha … See more Stathmin's role in regulation of the cell cycle causes it to be an oncoprotein named oncoprotein 18 (op18). Stathmin (aka op18) can cause … See more • Sobel A (August 1991). "Stathmin: a relay phosphoprotein for multiple signal transduction?". Trends in Biochemical Sciences. 16 (8): 301–5. doi:10.1016/0968-0004(91)90123-D See more blue microphones ember condenser microphone