WebCoarse C-screen or suspended V-screen TFF device configurations should be applied for medium (5–10 X) to higher concentration (30–50 X) activities; TFF process optimization is required, however. Optimizing the Transmembrane Pressure and Flux. In terms of parameters, a lower TMP is favored. WebA Repligen-exclusive technology, the Automatic Back Pressure Control Valve adds transmembrane pressure (TMP) control to every TFF process, reducing operator hands-on-time and improving process reproducibility. Automatically adjust tubing pinch distance according to user-defined set-points
TFF - Levitronix
http://www.ebiotrade.com/custom/Pall/120518/images/%E9%A2%87%E5%B0%94%E5%88%87%E5%90%91%E6%B5%81%E8%B6%85%E6%BB%A4%E7%B3%BB%E7%BB%9F%E6%89%8B%E5%86%8C.pdf WebOverview The fully automated Cogent ® TFF system is designed to separate and purify monoclonal antibodies, vaccines, plasma, and therapeutic proteins. It is ideally suited for both pilot and production scale applications, thereby supporting rapid scale up from small to large scale operations. 2b最后复活了吗
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WebTypical TFF system critical flush volumes of 20 L/m2 of membrane are used and should yield TOC values below a 1.0 ppm level. The procedures are summarized as follows: • Fill clean tank with water-for-injection (WFI) • Divert permeate and retentate lines • Set standard flush conditions • Sample flush water over time • Measure TOC WebSIUS ® Cassettes are the first purpose-built single-use cassettes for tangential flow filtration, delivering unparalleled savings in filter cost, labor cost and buffer use. TangenX ® PRO Cassettes Designed to be cleaned and re-used multiple times, PRO and PRO PD Reusable TFF Cassettes are interchangeable with SIUS ® Single-use Cassettes. WebTransmembrane Pressure (TMP) The relationship between flux and transmembrane pressure can be understood by generating a TMP versus a flux curve: The first part of the … 2b期研究